Pharmacological efficacy models
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Monkeys ：
Capsaicin-Induced Thermal Allodynia Model
Chronic MPTP Treatment Model for typical anti-PD agents
・Assay (Total) IgE Levels in Serum
・Assay Cytokine Levels
・Transient Occlusion
・Estimate the neutrophils infiltration in Bronchial Alveolar Lavage Fluid (BALF)
・Assay Cytokine Levels
・Measure the chord length of the alveolar (Histology)
Bleomycin-Induced Fibrosis Models
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AV Shunt Model
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Mosconi&Kruger (M&K) Model
Rodents ：
Acute / Chronic Asthma Models ;
OVA-Induced Model / House Dust Mite-Induced Model
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・Photochemical-Induced Thrombosis Model
HAMAMATSU PHARMA RESEARCH
TEL：＋81-53-543-4543 FAX：＋81-53-543-6444
Photochemical Induced Thrombosis Model
Evaluation with MRI, CT also available.
・Estimate the neutrophils infiltration in Bronchial Alveolar Lavage Fluid (BALF)
・Assay Cytokine Levels
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.Acute MPTP Treatment Model for Neuroprotectants (Hemi-PD Model)
Segmental Spinal Nerve Ligation (SNL) Model ※Chung Model
Macrophages / Monocytes
Emphysema (COPD) Models ： LPS-Indeced Model / Elastase-Indeued Model
e-mail：info@hpharma.jp
DSS (Dextran Sulfate Sodium) Model
・Estimate the neutrophils infiltration in Bronchial Alveolar Lavage Fluid (BALF)
・Estimate the airway remodeling (Measure the thickness of airway wall)
・It is possible to induce eosinophilic inflammation without using adjuvant
such as
Al (OH) gel
(It is available to estimate chronic asthma response)
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Spleen cells, Lymph node cells (T cells, Antigen presenting cells (APC))
1-3-7Kita-ku Shinmiyakoda, Hamamatsu,
Shizuoka, 431-2103 JAPAN
TNBS (Trinitrobenzene sulfonic acid) Model
Chronic Constriction Injury (CCI) Model ※Bennet Model
Partial Sciatic Nerve Injury (PSL) Model ※Selzer Model
FeCl Induced Thrombosis Model
Middle Cerebral Artery (MCA) Occlusion Models
Pharmacological efficacy models
MIA-Induced OA Model
Spinal cord Injury Pain Model
TNBS-Induced Visceral Hypersensitivity Model
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・Permanent Occlusion Model